Dose stepsOct 1, 2026
Ozempic tablets dose steps: 1.5, 4 and 9 mg
Thirty days at 1.5, thirty at 4, then 4 or 9. The label's schedule for the tablet that replaced Rybelsus.
Oral semaglutide · Novo Nordisk
Ozempic tablets, from the label
The once-daily semaglutide tablet for type 2 diabetes, in US pharmacies since May 4, 2026. It replaces Rybelsus, with the same morning rules and half the dose numbers. Everything on this page comes from the prescribing information.
Written by DM, the one who read the label. Sources checked Sep 28, 2026.
How to take it
Every morning, on an empty stomach, with a sip of plain water, then at least 30 minutes before anything else. The same rule as Rybelsus and as the Wegovy pill.
The dose steps
Three strengths: 1.5 mg for days 1 to 30, 4 mg for days 31 to 60, then 4 or 9 mg. They match the Rybelsus strengths under new numbers, and the label says the two are not interchangeable milligram for milligram.
From the labelRYBELSUS and OZEMPIC tablets are not substitutable on a mg-to-mg basis. OZEMPIC Tablets: Day 1 to 30: Recommended starting dosage is 1.5 mg orally once daily for 30 days (this dosage is not effective for glycemic control). Days 31 to 60: Increase the dosage to 4 mg orally once daily.
Rybelsus and Ozempic tablets prescribing information, §2.1 and §2.2, revised 1/2026
If a dose is missed
From the labelIf a dose is missed, skip the missed dose and take the next dose the following day.
Rybelsus is retired
Rybelsus was discontinued in the United States on May 4, 2026 and replaced by Ozempic tablets. A bottle of Rybelsus still in the cupboard is the same molecule at the old numbers.
Sources
- Rybelsus prescribing information, Novo Nordisk
- Rybelsus brand retired in the US, Ozempic pill takes over, Fierce Pharma
- Rybelsus discontinued, replaced by Ozempic tablets, Priority Health provider notice, 2026-08-31
This page is information, not medical advice. Read the medical disclaimer.
Draw it
The half-life above, turned into a curve you can play with: the pill level chart, eight weeks of mornings, tap the ones you missed.
Questions about the Ozempic® tablets
All answers
Oolite
The GLP-1 tracker for the pill and the shot.
The 30 minute timer, your shot day, the level chart and the dose reminder, on iPhone, with Apple Watch to log. Free to download, then a 14-day free trial.