Side effectsOct 11, 2026
Foundayo and low blood sugar
Two percent with type 2 diabetes, seven with a sulfonylurea, under one without diabetes. The label's numbers and its list of signs.
Orforglipron · Eli Lilly
Foundayo, from the label
A once-daily orforglipron tablet for weight management, approved on April 1, 2026. It is not a peptide, and the label sets no rule about food or water. Everything on this page comes from the prescribing information.
Written by DM, the one who read the label. Sources checked Sep 28, 2026.
How to take it
Once a day, at any time of day, with or without food. There is no morning window and no water limit: the rules of the semaglutide pills do not apply here.
From the labelTake FOUNDAYO orally once daily, with or without food. Swallow tablets whole. Do not break, crush, or chew. Do not take more than one tablet per day.
The dose steps
Six strengths: 0.8 mg for at least 30 days, then 2.5 mg for at least 30 days, then 5.5 mg. From there the prescriber may move to 9, 14.5 or 17.2 mg, each after at least 30 days on the current strength, based on response and tolerability.
From the labelThe starting dosage is 0.8 mg orally once daily. After at least 30 days on the 0.8 mg dosage, increase the dosage to 2.5 mg once daily. After at least 30 days on the 2.5 mg dosage, increase the dosage to 5.5 mg once daily. The dosage may be increased to the next dosage level (9 mg, 14.5 mg, or 17.2 mg once daily) after at least 30 days on the current dosage, based on treatment response and tolerability.
Foundayo prescribing information, §2 and §12.3, revised 07/2026
If a dose is missed
The rule is the opposite of the semaglutide pills: a missed Foundayo dose is taken as soon as it is remembered.
From the labelIf a dose is missed, instruct patients to take the dose as soon as possible. Advise patients not to double up the next dose. If 7 or more consecutive doses are missed, reinitiate dosage escalation at a lower dosage to reduce the risk of gastrointestinal adverse reactions.
How long it stays in the body
Orforglipron leaves the body much faster than semaglutide. Taken once a day, the level settles after about a week on the same strength.
From the labelThe elimination half-life is approximately 29 to 49 hours after an oral dose. Steady state exposure is achieved after approximately 1 week of once daily administration.
Sources
- Foundayo prescribing information, Eli Lilly, revised 07/2026
- FDA approves Lilly's Foundayo, press release, April 2026
This page is information, not medical advice. Read the medical disclaimer.
Draw it
The half-life above, turned into a curve you can play with: the pill level chart, eight weeks of mornings, tap the ones you missed.
Questions about the Foundayo™
All answers
Side effectsOct 11, 2026
Foundayo side effects, dose by dose
The label's table, strength by strength: nausea, constipation, diarrhea, vomiting, and the sentence about escalation.
Everyday lifeOct 9, 2026
Can I take Foundayo at night, or with dinner?
No morning window, no water rule, no waiting. What the label does ask for, and why a fixed time helps with this molecule.
Everyday lifeOct 7, 2026
How to store Foundayo
Room temperature, and nothing about light any more: what the July 2026 label changed, and the range that is safe on a hot day.
Dose stepsOct 6, 2026
The first week on Foundayo
What the label says the first days are: 0.8 mg, any time, settled in a week, stomach effects higher during the escalation.
Dose stepsOct 6, 2026
The Foundayo dose schedule, from 0.8 to 17.2 mg
Three fixed steps, then three the prescriber chooses. At least 30 days each, 17.2 mg at most.
Everyday lifeOct 3, 2026
Can I take Foundayo with food?
With or without food, says the label, and here is the study behind those four words.
Missed dosesOct 3, 2026
What if I missed a dose of Foundayo?
Take it as soon as you remember, never double up, and a seven day rule the Wegovy pill does not have.
Oolite
The GLP-1 tracker for the pill and the shot.
The 30 minute timer, your shot day, the level chart and the dose reminder, on iPhone, with Apple Watch to log. Free to download, then a 14-day free trial.